本書正文共分五部分，包括總論；生物分子的結構和功能(蛋白質、核酸、糖結合物、酶、維生素)；代謝與調控(碳水化合物、脂質和氨基酸的代謝、生物氧化、核苷酸代謝、血液生物化學、肝膽生物化學、代謝的整合與調控)；信息途徑(DNA合成、DNA損傷與修復、RNA合成、蛋白質合成、基因表達調控、細胞信號轉導)和分子醫(yī)學(組學基本原理、基本分子生物學技術、應用：癌基因和抑癌基因、基因診斷和基因治療、基因工程藥物和疫苗)。在每一章中，我們在開頭列出了概述，并在每章末尾提供了摘要、關鍵術語、關鍵概念圖、問題和進一步閱讀，圖文并茂，具有較高的學術價值。
Introduction
Chapter 1 Structure and Function of Proteins
1.1 Molecular composition of proteins
1.2 Molecular structure of proteins
1.3 Structure-function relationship of proteins
1.4 Working with proteins
Chapter 2 Structure and Function of Nucleic Acids
2.1 Components and primary structure of nucleic acids
2.2 Spatial structure and function of DNA
2.3 Structure and function of RNA
2.4 Physical and chemical properties of nucleic acids
Chapter 3 Structure and Function of Glycoconjugates
3.1 Glycans and their synthetic process in glycoproteins
3.2 Glycosaminoglycans in proteoglycan molecules
3.3 Glycolipids are involving glycosphingolipids, glyceroglycolipids, and steroid-derived glycolipids
3.4 Glycan structure indicates rich biological information
Chapter 4 Enzyme
4.1 The structure and function of enzymes
4.2 Mechanism of enzyme action
4.3 Enzyme kinetics
4.4 The regulation of enzymes
4.5 Enzyme nomenclature
4.6 Connecting enzyme and medicine
Chapter 5 Vitamins
5.1 Lipid-soluble vitamins
5.2 Water-soluble vitamins
Chapter 6 Carbohydrate Metabolism
6.1 Digestion,absorption,and transport of glucose
6.2 Anaerobic oxidation of glucose
6.3 Aerobic oxidation of glucose
6.4 Pentose phosphate pathway
6.5 Glyeogenesis and glycogenolysis
6.6 Gluconeogenesis
6.7 Other metabolic pathways of glucose
6.8 Regulation of blood glucose
Chapter 7 Biological Oxidation
7.1 Electron transport chain
7.2 Oxidative phosphorylation
7.3 Regulation of oxidative phosphorylation
7.4 Other biological oxidations without ATP production
Chapter 8 Lipid Metabolism
8.1 Overview of lipids
8.2 The digestion and absorption of dietary lipids
8.3 Metabolism of triglycerides
8.4 Metabolism of glycerophospholipids
8.5 Metabolism of cholesterol
8.6 Plasma lipoprotein metabolism
Chapter 9 Amino Acid Metabolism
9.1 The physiological function and nutritive value of proteins
9.2 Sources of amino acids in vivo
9.3 General metabolism of amino acids
9.4 Metabolism of ammonia
9.5 Metabolisms of individual amino acids
Chapter 10 Nucleotide Metabolism
10.1 Overview of nucleotides metabolism
10.2 Biosynthesis and degradation of purine nucleotides
10.3 Biosynthesis and degradation of pyrimidine nucleotides
10.4 Abnormal nucleotide metabolism and nucleotide antimetabolites
Chapter 11 Blood Biochemistry
11.1 Plasma proteins
11.2 Synthesis of hemoglobin
11.3 Metabolism of blood cell
Chapter 12 Liver Biochemistry
12.1 The roles of liver in metabolism
12.2 Hepatic biotransformation
12.3 Metabolism of bile acids
12.4 Metabolism of the bile pigment
Chapter 13 Integration and Regulation of Metabolism
13.1 The relation and integration of metabolism
13.2 The major ways of regulation of metabolism
13.3 Characteristic of metabolism in different organs
13.4 The abnormal metabolism in diseases
Chapter 14 DNA Synthesis
14.1 Fundamental rules of DNA replication
14.2 Various enzymes and proteins are involved in DNA replication
14.3 Prokaryotic DNA replication
14.4 Eukaryotic DNA replication
14.5 Reverse transcription and other models of DNA replication
Chapter 15 DNA Damage and Repair
15.1 DNA damage
15.2 DNA repair
15.3 Significance of DNA damage and repair
Chapter 16 RNA Synthesis
16.1 Template,enzymology and mechanism of RNA transcription
16.2 Transcription in prokaryotes
16.3 Transcription in eukaryotes
16.4 RNA processing in eukaryotes
Chapter 17 Protein Biosynthesis
17.1 Molecules involved in protein synthesis
17.2 The process of protein synthesis
17.3 Posttranslational processing of protein and targeting
17.4 Protein synthesis and clinical correlates
Chapter 18 Regulation of Gene Expression
18. 1 Basic concepts and principle of gene expression and regulation
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