目 錄

第一章 解答有機(jī)合成題的基礎(chǔ)知識(shí)準(zhǔn)備················································································ 1

一、烴類和簡單雜環(huán)的官能團(tuán)化····························································································· 1

二、官能團(tuán)的轉(zhuǎn)換················································································································ 6

三、復(fù)習(xí)和熟練掌握碳鏈的增長方法······················································································ 9

四、熟悉一些重要的重排反應(yīng)······························································································ 10

五、掌握碳碳鍵的構(gòu)建方法·································································································· 10

六、掌握化學(xué)鍵的切斷與逆合成分析法················································································· 10

七、熟悉按照化學(xué)鍵異裂方式切斷后的常見合成子及其對應(yīng)的等價(jià)物······································· 10

八、逆合成分析切斷法的技巧······························································································ 11

九、一條理想的合成路線的確定需要把握的幾點(diǎn)···································································· 11

第二章 有機(jī)化合物常見增長和縮短碳鏈的方法····································································· 12

第一節(jié) 增長碳鏈的方法····································································································· 12

一、增加一個(gè)碳原子的常見方法··························································································· 12

二、增加兩個(gè)碳原子的常見方法··························································································· 16

三、增加三個(gè)碳原子的常見方法··························································································· 19

四、增加四個(gè)碳原子的常見方法··························································································· 22

五、碳鏈倍增法·················································································································· 22

第二節(jié) 縮短碳鏈的方法····································································································· 24

一、減少一個(gè)碳原子的常見方法··························································································· 24

二、烯烴通過氧化斷鍵減少一個(gè)或多個(gè)碳的方法···································································· 25

第三章 有機(jī)合成練習(xí)題題解······························································································· 26

參考文獻(xiàn)·························································································································· 238