This guide includes 25 chapters divided into four parts : Structure and
function of biomolecule ( Part Ⅰ), Metabolism and regulation ( Part Ⅱ),
Information pathways ( Part Ⅲ) and Molecular medicine ( Part Ⅳ).
There are three portions in each chapter: Examination syllabus, Major
points and Practices. Firstly the examination syllabus for MLE (Medical
Licensing Examination) is provided. Then the major points are connected
in a conceptual framework by making mind maps, and using words, figures
and tables refined.Finally, multiple choice questions (A1, A2, B1,
X-type) and some clinical case problems are supplied for practice and
testing the learning effect.
This book is suitable for
undergraduate students in medical schools ( especially Bachelor of
Medicine & Bachelor of Surgery, MBBS) to review major concepts and
information while also preparing for course exams, MLE, and the
postgraduate entrance exam. This book can also be used as a teaching
reference bookfor biochemistry teachers as well as a reference book of
continuing education for relevant professionals.
Part Ⅰ STRUCTURE AND FUNCTION OF BIOMOLECULE
Chapter 1 Structure and Function of Proteins
Ⅰ.Amino acids and Peptides
Ⅱ.Protein Structure
Ⅲ.Protein Function
Ⅳ.Working with proteins
Chapter 2 Structure and Function of Nucleic Acids
Ⅰ.Nucleic acid
Ⅱ.Structure and function of DNA
Ⅲ.Structure and function of RNA
Ⅳ.Physical and chemical properties of nucleic acids and their applications
Chapter 3 Structure and Function of Glycoconjugates
Ⅰ.Glycans in glycoproteins
Ⅱ.Glycosaminoglycans in proteoglycan molecules
Ⅲ.Glycolipids
Ⅳ.Functions of Glycan structure
Chapter 4 Enzyme
Ⅰ.General Properties of Enzymes
Ⅱ.Mechanism of Enzyme Action
Ⅲ.Enzyme kinetics
Ⅳ.Regulation of enzyme
Chapter 5 Vitamins
Ⅰ.Lipid-soluble vitamins
Ⅱ.Water-soluble vitamins
Part Ⅱ METABOLISM AND REGULATION
Chapter 6 Carbohydrate metabolism
Ⅰ.The anaerobic oxidation of glucose
Ⅱ.Aerobic oxidation
Ⅲ.Pentose phosphate pathway
Ⅳ.Glycogen metabolism
Ⅴ.Gluconeogenesis
Ⅵ.Blood glucose and the regulation
Chapter 7 Biological Oxidation
Ⅰ.Electron transport chain
Ⅱ.Oxidative phosphorylation and ATP synthesis
Ⅲ.Regulation of oxidative phosphorylation
Ⅳ.Selective transport across the inner mitochondrial membrane
Ⅴ.Other biological oxidations without ATP producing
Chapter 8 Metabolism of Lipids
Ⅰ.The physiological function of lipids
Ⅱ.Digestion and absorption of fats
Ⅲ.Anabolism of triacylglycerol
Ⅳ.Synthesis of fatty acids
Ⅴ.Fat catabolism
Ⅵ.Metabolism of glycerophospholipids
Ⅶ.Cholesterol metabolism
Ⅷ.Plasma lipoprotein metabolism
Chapter 9 Metabolism of Amino acid
Ⅰ.The physiological function and nutritive value of protein
Ⅱ.Digestion, absorption and putrefaction of the protein in the intestinal tract.
Ⅲ.General metabolism of amino acids
Ⅳ.Metabolism of ammonia
Ⅴ.Metabolisms of individual amino acid
Chapter 10 Nucleotide Metabolism
Ⅰ.Functions of nucleotides
Ⅱ.Synthesis and degradation of purine nucleotides
Ⅲ.Synthesis and degradation of pyrimidine nucleotides
Chapter 11 Blood Biochemistry
Ⅰ.Plasma proteins
Ⅱ.Synthesis of hemoglobin
Ⅲ.Metabolism of red blood cell and leukocyte
Chapter 12 Liver Biochemistry
Ⅰ.The Role of Liver in Metabolism
Ⅱ.Hepatic Biotransformation
Ⅲ.Bile and the metabolism of bile acid
Ⅳ.Metabolism of bile pigment
Chapter 13 Integration and Regulation of Metabolism
Ⅰ.The relationralation and integration of metabolism
Ⅱ.The major manner of regulation of metabolism
Ⅲ.Characteristic of metabolism in different organs
Ⅳ.The abnormal metabolism in disease
Part Ⅲ INFORMATION PATHWAYS
Chapter 14 DNA Synthesis
Ⅰ.Three basic rules of DNA replication
Ⅱ.Various enzymes and proteins involved in DNA replication
Ⅲ.Prokaryotic DNA replication
Ⅳ.Eukaryotic DNA replication
Ⅴ.Reverse Transcription and Other Models of DNA Replication
Chapter 15 DNA Damage and Repair
Ⅰ.DNA damage
Ⅱ.DNA repair
Ⅲ.Significance of DNA damage and repair
Chapter 16 RNA Synthesis
Ⅰ.Introductiont of RNA biosynthesis
Ⅱ.The process of RNA synthesis process
Ⅲ.Post-transcriptional processing
Chapter 17 Protein Synthesis
Ⅰ.The concept of protein biosynthesis
Ⅱ.Protein biosynthesis system and genetic code
Ⅲ.The basic process of protein biosynthesis
Ⅳ.The relationship between protein biosynthesis and medicine
Chapter 18 Regulation of Gene Expression
Ⅰ.Gene expression
Ⅱ.Mechanism of gene regulation
Chapter 19 Signal Transduction
Ⅰ.Extracellular signal molecules
Ⅱ.Receptors and signal transduction molecules
Ⅲ.Membrane receptor-mediated intracellular signal transduction
Ⅳ.Int
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